Effect of Chemotherapy on Taste Sensation in Patients with Disseminated Malignant Melanoma
作者:
N.H. Mulder,
J.M. Smit,
W.M.I. Kreumer,
J. Bouman,
D.T. Sleijfer,
W. Veeger,
Schraffordt Koops,
期刊:
Oncology
(Karger Available online 1983)
卷期:
Volume 40,
issue 1
页码: 36-38
ISSN:0030-2414
年代: 1983
DOI:10.1159/000225687
出版商: S. Karger AG
关键词: Anorexia;Taste;Cancer chemotherapy;Malignant melanoma
数据来源: Karger
摘要:
The effect of combination chemotherapy (bleomycin, actinomycin D, vindesine and DTIC) on taste sensation in patients with malignant melanoma was evaluated. Five concentrations of 4 basic tastes (sweet, bitter, sour and salt) were tested. Lowest concentrations of all tastes were subjectively rated more intense after chemotherapy than before. This change was significant for sweet, sour and salt. The highest concentration of sweet was rated significantly less intense following chemotherapy. The discrimination between highest and lowest concentration was diminished for sweet, sour and bitter and marginally for salt. The changes in taste sensation following chemotherapy could attribute to anorexia in cancer patients treated with cytostatic agents.
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