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Magnetic Resonance Imaging Correlates of Executive Function Impairments in Multiple Sclerosis

 

作者: Steven Huber,   Robert Bornstein,   Kottil Rammohan,   Jeffrey Christy,   Donald Chakeres,   Robert McGhee,  

 

期刊: Neuropsychiatry, Neuropsychology & Behavioral Neurology  （OVID Available online 1992）
卷期: Volume 5, issue 1  

页码: 33-36

 

ISSN:0894-878X

 

年代: 1992

 

出版商: OVID

 

关键词: Multiple sclerosis;Executive function;Magnetic resonance imaging

 

数据来源: OVID

 

摘要:

Frontal lobe lesions may play an integral role in cognitive impairments associated with multiple sclerosis (MS). Executive function impairments, traditionally linked to frontal lobe lesions, are common neuropsychological deficits in MS. We found that executive functions were related to left frontal lesions, and to the total brain lesion area. This pattern suggests that left frontal lesions and/or disruption of the pathways to the left frontal lobe have a role in these disturbances in MS.

 

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