Ceftriaxone Single Dose versus Ceftazidime Multiple Doses in the Prophylaxis of Infection in Colorectal Surgery
作者:
J. Palla Garcia,
Consiglieri Pedroso,
期刊:
European Surgical Research
(Karger Available online 1989)
卷期:
Volume 21,
issue 1
页码: 14-18
ISSN:0014-312X
年代: 1989
DOI:10.1159/000129054
出版商: S. Karger AG
关键词: Infection prophylaxis;Colorectal surgery;Ceftriaxone;Ceftazidime
数据来源: Karger
摘要:
Sixty patients admitted to the hospital for colorectal surgery were randomly assigned to prophylaxis either with a single dose of ceftriaxone (Rocephin®) i.v. plus metronidazole given 30 min prior to induction of anesthesia or with multiple doses of ceftazidime plus metronidazole given repeatedly every 8 h up to 24 h after surgery. The overall number of infections observed with the long-acting cephalosporin ceftriaxone was 4 (2 local and 2 remote), with the short-acting ceftazidime the number was 9 (5 local and 4 remote). Neither regimen was associated with adverse reactions
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