Forty-four women using either Demulen, Deladroxate, or an intrauterine device for contraceptive purposes were studied for urinary tract disorders. Excretory urograms and serum creatinines were performed before contraception was initiated and thereafter at six-cycle intervals. Monthly urine specimens were cultured and examined cytologically. No effect on the urinary tract was noted by X-ray studies and the creatinines all remained normal. Cytologic studies also revealed no abnormalities. The incidence of positive urine cultures was 6.8% initially and 11% during the course of study. Only one woman developed symptoms of infection. A review of the urograms of patients followed in the Family Planning Clinic indicated that dilatation of the upper urinary tract cannot be attributed to anovulatory drugs.