This article describes the methods used, problems encountered, and solutions that were generated while integrating Web-based instruction (WBI) into a Master of Science in Nursing Leadership and Case Management, and a Post-Master's Case Management certificate distance education program taught via videoconferencing. The writer describes the use of computer-mediated communication to enhance collaboration between and among students at 11 videoconferencing sites. The integration of WBI to support collaboration was successful because students and faculty could complete their academic activities in the locations and times that were most convenient to them. The tools that WBI provided were instrumental in helping students submit collaborative work that faculty often identified as far exceeding their expectations.