SummaryThe authors reported a case of “pseudo‐ulegyric type” of hepatocerebral disease.1) Clinical course: A male aged 21 at the time of death. The patient had unbalanced diet. The illness began with insomnia and confusional state during the night. Recurring periods of clouding of consciousness lasting several hours were noted. About 5 months after the onset, he became bedridden and showed incontinence. In the later stage the intermittent periods of normality became shorter, and muscular rigidity set in in four limbs. Emaciation was marked, and he regressed mentally. Liver function test showed a slight degree of damage. Death occurred about one year after the onset of the disease.2) Pathological examination showed pseudo‐ulegyric change as well as laminar cortial necrosis in the insula, T.2, T.3 and temporo‐occipital regions on both sides, which were marked in the bottom of the sulci. Alzheimer's type II of glial cells were found diffusely in the cerebral cortex, in the nucleus of which Carmin‐positive substance was found.3) Clinico‐pathological comparison was made with 6 cases in t