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Change in Human Electroretinography Associated with Thioridazine Administration

 

作者: Mikio Miyata,   Hiroko Imai,   Satoshi Ishikawa,   Sadao Nakajima,  

 

期刊: Ophthalmologica  （Karger Available online 1980）
卷期: Volume 181, issue 3-4  

页码: 175-180

 

ISSN:0030-3755

 

年代: 1980

 

DOI:10.1159/000309049

 

出版商: S. Karger AG

 

关键词: Electroretinography;Oscillatory potentials;Thioridazine

 

数据来源: Karger

 

摘要:

28 patients treated with thioridazine (TZ) were examined by electroretinography (ERG). The most characteristic feature was a decrease in amplitudes of the oscillatory potentials O2, O3 and O4. A significant correlation was observed between the daily dosage of TZ and the diminished amplitude as well as the delayed peak time of the O2 wavelet. When a dose of 400 mg/day of TZ was administered during a short time, similar ERG changes were induced.

 

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