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A Phase II Study of Cisplatin in Patients with Biliary Tract Carcinoma

 

作者: Shuichi Okada,   Hiroshi Ishii,   Haruhiko Nose,   Masayoshi Yoshimori,   Takuji Okusaka,   Kazunori Aoki,   Masahiko Iwasaki,   Junji Furuse,   Masahiro Yoshino,  

 

期刊: Oncology  （Karger Available online 1994）
卷期: Volume 51, issue 6  

页码: 515-517

 

ISSN:0030-2414

 

年代: 1994

 

DOI:10.1159/000227396

 

出版商: S. Karger AG

 

关键词: Cisplatin;Biliary tract carcinoma;Chemotherapy

 

数据来源: Karger

 

摘要:

A phase II study of cisplatin was performed in 13 previously untreated patients with unresectable biliary tract carcinoma. The drug was given intravenously at a dose of 80 mg/m2/day once every 4 weeks. Of 13 patients evaluated, 1 showed partial response lasting 3 months, while no patient showed complete response. Of 9 patients, whose serum level of carcinoembryonic antigen (CEA) was high (≥10 ng/ml) before treatment, 4 showed ≥50% reduction in serum CEA level after treatment. The current study indicates that cisplatin does not have significant antitumor activity against biliary tract carcin

 

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