Influence of Aspirin on Healing of Chronic Gastric Ulcers in Dogs
作者:
K. Takeuchi,
S. Okabe,
K. Takagi,
N. Umeda,
期刊:
Digestion
(Karger Available online 1977)
卷期:
Volume 16,
issue 1-2
页码: 51-56
ISSN:0012-2823
年代: 1977
DOI:10.1159/000198055
出版商: S. Karger AG
关键词: Acetic acid;Aspirin;Dogs;Gastric mucosa;Peptic ulcer
数据来源: Karger
摘要:
Gastric ulcers induced in dogs by transserosal injection of 1 ml of 40% acetic acid healed completely by the 7th week after ulceration and never reulcerated during the observation period up to 12 weeks. Acetic acid ulcers in the active (at 1 week), quiescent (3 weeks) or healed (at 7 weeks) stages were not influenced by the daily administration of aspirin 2 g/dog/day for 5 consecutive weeks. All examinations were done by gastroscopy in addition to macroscopical and histological observations at autopsy.
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