Mechanisms of hypoglycemic activity of panaxans A and B, glycans ofPanax ginsengroots: Effects on the key enzymes of glucose metabolism in the liver of mice
作者:
Yutaka Suzuki,
Hiroshi Hikino,
期刊:
Phytotherapy Research
(WILEY Available online 1989)
卷期:
Volume 3,
issue 1
页码: 15-19
ISSN:0951-418X
年代: 1989
DOI:10.1002/ptr.2650030105
出版商: John Wiley&Sons, Ltd.
关键词: Panax ginseng;Araliaceae;panaxans A and B;glycans;hypoglycemic activity;glucose metabolism
数据来源: WILEY
摘要:
AbstractPanaxan A did not affect the activities of hepatic glucokinase and hexokinase but decreased glucose‐6‐phosphatase activity. Although panaxan B did not influence the activities of these enzymes, it showed a tendency to reduce hepatic glycogen synthetase activity, and panaxans A and B elevated the phosphorylase activity. Panaxan B lowered the glycogen content in the liver. Panaxans A and B significantly increased the activities of glucose‐6‐phosphate dehydrogenase and phosphofructokinase in th
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