Verticillium Peritonitis in a Patient on Peritoneal Dialysis
作者:
Gianpaolo Amici,
Stefano Grandesso,
Attilio Mottola,
Giovambattista Virga,
Teodoro Teodori,
Maria Cristina Maresca,
Carlo Bocci,
期刊:
American Journal of Nephrology
(Karger Available online 1994)
卷期:
Volume 14,
issue 3
页码: 216-219
ISSN:0250-8095
年代: 1994
DOI:10.1159/000168718
出版商: S. Karger AG
关键词: Fungal peritonitis;Peritoneal dialysis;Verticillium
数据来源: Karger
摘要:
We describe a case of peritonitis due to Verticillium spp. in a 33-year-old farmer on continuous ambulatory peritoneal dialysis (CAPD) for 3 months for end-stage renal failure due to chronic pyelonephritis. The etiologic agent was a hyaline hyphomycete which we report as a new human opportunistic pathogen. The fungus was isolated from the peritoneal fluid culture and from the tip of the catheter; identification was made on the basis of macroscopic and microscopic features. The patient had previously been admitted to our hospital for peritonitis caused by mixed enteric flora and treated for 8 days with intraperitoneal broad-spectrum antibiotic therapy. Five days after discharge he was readmitted for severe abdominal pain and cloudy drainage fluid. Two days of intraperitoneal broad-spectrum antimicrobial therapy produced no clinical improvement. Intravenous fluconazole and oral flucytosine were administered upon identifying the fungus. After another 2 days without improvement, peritoneal dialysis was discontinued and the catheter removed. Antimycotic therapy was continued for 4 days with complete resolution of the peritonitis. The patient chose to start hemodialysis and was discharged in good clinical condition.
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