Immunological status of trophoblastic neoplasia
作者:
A. Khanna,
S. Khanna,
R. M. Gupta,
S. Gupta,
A. K. Khanna,
期刊:
Journal of Surgical Oncology
(WILEY Available online 1985)
卷期:
Volume 28,
issue 1
页码: 4-6
ISSN:0022-4790
年代: 1985
DOI:10.1002/jso.2930280103
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: choriocarcinoma;vesicular mole;trophoblast;immunity
数据来源: WILEY
摘要:
AbstractSix cases of choriocarcinoma, 17 of vesicular mole, 20 normal pregnant females in the first trimester of pregnancy, and 20 normal nonpregnant women with previous normal obstetrical history were evaluated quantitatively for cell‐mediated immunity by response to 2:4 dinitrocholoroben‐zene and recall antigens. Serum immunoglobulins were estimated in all cases. Suppression of cell‐mediated immunity was marked in choriocarcinoma as compared to vesicular mole. Serum IgG levels were significantly diminished in cases of vesicular mole, indicating diminished humoral immunity. Follow‐up after 3 months of treatment with surgery and chemotherapy resulted in marked improvement of cell‐mediated
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