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Comparison of Tinidazole Given as a Single Dose and on 2 Consecutive Days for the Treatment of Nonspecific Bacterial Vaginosis

 

作者: Josef Ekgren,   Berit K. Norling,   Miklos Degre,   Tore Midtvedt,  

 

期刊: Gynecologic and Obstetric Investigation  （Karger Available online 1988）
卷期: Volume 26, issue 4  

页码: 313-317

 

ISSN:0378-7346

 

年代: 1988

 

DOI:10.1159/000293712

 

出版商: S. Karger AG

 

关键词: Bacterial vaginosis;Clue cells;Gardnerella vaginalis;Tinidazole

 

数据来源: Karger

 

摘要:

Nonspecific bacterial vaginosis, defined as the presence of clue cells, was treated in a randomized, double-blind study with (1) tinidazole 2g as a single dose (82 patients), (2) tinidazole 2 g on 2 consecutive days (84 patients), and (3) with placebo (81 patients). The cure rates, both clue cells and Gardnerella vaginalis absent, were 51, 74 and 4%, respectively. A closer clinical and microbiological evaluation showed the 2-day regimen to be superior.

 

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