MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION ANDTRANSPLANTATION IMMUNITY A POSSIBLE SOLUTION TO THE ALLOGRAFT PROBLEM
作者:
WILLYS SILVERS,
HONG-DUO CHEN,
HILARI FLEMING,
ALI NAJI,
CLYDE BARKER,
STEPHEN BARTLETT,
期刊:
Transplantation
(OVID Available online 1984)
卷期:
Volume 37,
issue 1
页码: 28-32
ISSN:0041-1337
年代: 1984
出版商: OVID
数据来源: OVID
摘要:
Studies of the survival of weakly histoincompatible skin grafts in which the Langerhans' cells (LC)5have been replaced with major histocompatibility complex (MHC)-compatible or incompatible LC, as well as studies of the fate of cultured endocrine allografts in MHC-compatible and incompatible mice and rats, indicate that allografts are only recognized as foreign if they possess donor macrophages (or cells of this family), or if antigen presenting cells MHC-compatible with the graft can be provided by the host.
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