Resonance Raman studies on transient molecules have raised a problem about characterization of a photolabile species. Therefore, in order to observe the Raman and absorption spectra of the same spatial region of the sample at the same time, we have constructed a novel device and applied it successfully to monitor the transient species involved in an enzymic reaction of horseradish peroxidase and in photodissociation of the carbon monoxide adduct of hemoglobin.