KINETIC STUDIES OF CORTISOL AND SYNTHETIC CORTICOSTEROIDS IN MAN
作者:
P. J. Fell,
期刊:
Clinical Endocrinology
(WILEY Available online 1972)
卷期:
Volume 1,
issue 1
页码: 65-72
ISSN:0300-0664
年代: 1972
DOI:10.1111/j.1365-2265.1972.tb00378.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYFollowing the rapid intravenous injection of corticosteroids (cortisol, prednisolone, betamethasone and betamethasone‐17‐valerate), the blood levels of each were estimated and the results analysed in a two‐compartment open model. The kinetic analysis revealed differences in distribution and elimination which could have important therapeuticimplications. A theory is presented for the marked differences seen, and the therapeutic importance of these is disc
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