Brain Noradrenergic Activity in Wakefulness and Paradoxical Sleep: The Effect of Clonidine
作者:
Jean-Michel Gaillard,
期刊:
Neuropsychobiology
(Karger Available online 1985)
卷期:
Volume 13,
issue 1-2
页码: 23-25
ISSN:0302-282X
年代: 1985
DOI:10.1159/000118157
出版商: S. Karger AG
关键词: Sleep;Wakefulness;Man;Rat;Clonidine;α2-Adrenoceptors
数据来源: Karger
摘要:
Several experiments in which the effects of clonidine (CLN) have been studied in the rat and in man are summarized. CLN inhibits paradoxical sleep (PS) both in the rat and in man. This inhibition is followed by a rebound, but with a different time course in the two species. Wakefulness (W) is enhanced after some critical doses of CLN, and decreased after higher doses. These effects of CLN suggest that α2-adrenoceptors are involved in the regulation of W and PS
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