Pathophysiology and management of esophageal varices
作者:
Gerhard Kleber,
Tilman Sauerbruch,
期刊:
Current Opinion in Gastroenterology
(OVID Available online 1992)
卷期:
Volume 8,
issue 4
页码: 583-590
ISSN:0267-1379
年代: 1992
出版商: OVID
数据来源: OVID
摘要:
Esophageal varices are one of the most common and severe complications of chronic liver disease. New aspects in epidemiology, pathogenesis, and treatment of varices are reviewed. Sclerotherapy is the first-line treatment for acute hemorrhage. Prevention of first or recurrent bleeding is still unsatisfactory. β-Blockers are slightly superior to sclerotherapy with regard to prophylaxis of first bleeding. β-Blockers or sclerotherapy may be used for prophylaxis of recurrent bleeding. However, prophylactic treatment regimens do not have a major impact on survival. Combination treatment, new drugs, or new devices may help to improve the efficacy of prophylactic measures.
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