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Metabolic abnormalities and body fat redistribution in HIV-1 infected patients: the lipodystrophy syndrome

 

作者: Esteban Martínez,   José Gatell,  

 

期刊: Current Opinion in Infectious Diseases  (OVID Available online 1999)
卷期: Volume 12, issue 1  

页码: 13-19

 

ISSN:0951-7375

 

年代: 1999

 

出版商: OVID

 

数据来源: OVID

 

摘要:

A unique and unexpected syndrome consisting of metabolic abnormalities (hyperlipidaemia and insulin resistance) and body fat redistribution (central adiposity and peripheral fat wasting) has been reported with increasing frequency in HIV-1 infected patients, most of whom are receiving highly active antiretroviral therapies including HIV-1 protease inhibitors. This article reviews the clinical and laboratory characteristics, the pathogenesis, and the management of this syndrome.

 



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