Metabolic abnormalities and body fat redistribution in HIV-1 infected patients: the lipodystrophy syndrome
作者:
Esteban Martínez,
José Gatell,
期刊:
Current Opinion in Infectious Diseases
(OVID Available online 1999)
卷期:
Volume 12,
issue 1
页码: 13-19
ISSN:0951-7375
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
A unique and unexpected syndrome consisting of metabolic abnormalities (hyperlipidaemia and insulin resistance) and body fat redistribution (central adiposity and peripheral fat wasting) has been reported with increasing frequency in HIV-1 infected patients, most of whom are receiving highly active antiretroviral therapies including HIV-1 protease inhibitors. This article reviews the clinical and laboratory characteristics, the pathogenesis, and the management of this syndrome.
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