ABSTRACT:Chloral hydrate is one of the most frequently used sedatives in electroneurodiagnostic laboratories. Frequently, the technologists are responsible for administering it. They must, therefore, be trained to give it safely. This paper explores many of the issues involved in the safe use of chloral hydrate. The sedative dose in pediatrics is 25 mg/kg and no more than 1 gm should be given daily. Children should be monitored carefully while they are sedated and should not leave the hospital or clinic until awake. Parents must be given complete instructions on continued care until the sedation has completely worn off.