Serial hemodynamic studies have become increasingly important in hypertension research. These studies have been accomplished using the A-V shunt. The progressive decline in the number of A-V shunts in favor of the A-V fistula has limited the number of patients available for study. Although the A-V fistula can be used to measure cardiac output, the intra-arterial blood pressure cannot be measured through it. The present paper describes a technique formeasuring both the cardiac output and direct intra-arterial blood pressure using the bovineartegraft.