Gel electrophoresis (GE) is an important analytical technique in biology and medicine. The technique can be improved based on a better understanding of DNA structure and dynamics in the polymer network.Movement of fluorescence pattern after photobleaching (MOFPAP), together with its modified approaches, can measure stained DNA electrophoretic mobility in less time, permitting determinations of mobility (and probably velocity distribution) changes as a function of time during DNA chain deformations.