Topical betamethasone‐17‐valerate inhibits heat‐induced vasodilatation in man
作者:
A. AHLUWALIA,
R.J. FLOWER,
期刊:
British Journal of Dermatology
(WILEY Available online 1993)
卷期:
Volume 128,
issue 1
页码: 45-48
ISSN:0007-0963
年代: 1993
DOI:10.1111/j.1365-2133.1993.tb00146.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SummaryTopical betamethasone‐17‐valerate inhibits the vasodilatation response to local non‐pathological heating of rat skin.1We have shown that this effect can also be demonstrated in man. Topical betamethasone‐17‐valerate significantly inhibited the increase in human forearm cutaneous blood flow in response to heat of 44°C, as measured by laser‐Doppler velocimetry. This suggests that the effects of topical steroids upon skin blood flow in the rat and in man are similar, and supports the use of the animal model as a paradigm for studying human skin blood flow, and changes in response to anti‐inflamm
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