Long-Term Treatment with Sulphamethoxazole/Trimethoprim (Bactrim®) and Nitrofurantoin in Chronic Urinary Tract Infections
作者:
Jørgen Scherwin,
Per Holm,
期刊:
Chemotherapy
(Karger Available online 1977)
卷期:
Volume 23,
issue 4
页码: 282-288
ISSN:0009-3157
年代: 1977
DOI:10.1159/000221996
出版商: S. Karger AG
关键词: Bactrim;Nitrofurantoin;Long-term treatment;Urinary tract infections;Controlled trial
数据来源: Karger
摘要:
In a controlled clinical trial based on 30 geriatric patients with recurrent urinary tract infection, 12 out of 17 patients fulfilled a 12-month treatment with sulphamethoxazole/trimethoprim (Bactrim®) with continuous sterile urine compared to 1 out of 13 patients treated with nitrofurantoin (p < 0.05). There was a slight but statistically significant increase in serum creatinine during treatment for 12 months in the sulphamethoxazole/trimethoprim group, but this probably does not reflect any deterioration in kidney function. The remaining laboratory values showed no significant changes whatsoever
点击下载:
PDF
(1621KB)
返 回