&NA;Rapid advances are being made in gene mapping of colorectal cancer. Estimation of individual colorectal cancer risk based on such information is not far away. The debate over the real value of current screening techniques continues. There is general agreement that fecal occult blood testing with guaiac‐based tests is not perfect. Recommendations for screening based on family history and clinical characteristics are being refined. Endoscopy or radiographic examinations should replace fecal occult blood testing in high‐risk individuals. Such structural studies of the entire colon should also be considered in case detection of those at average risk.Current Opinion in Gastroenterology 1992,8:25‐30