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Amantadine Toxicity in a Patient with Renal Insufficiency

 

作者: K.F.W. Armbruster,   A.C. Rahn,   T.S. Ing,   I.S. Halper,   J.H. Oyama,   H.L. Klawans,  

 

期刊: Nephron  （Karger Available online 1974）
卷期: Volume 13, issue 2  

页码: 183-186

 

ISSN:1660-8151

 

年代: 1974

 

DOI:10.1159/000180391

 

出版商: S. Karger AG

 

关键词: Amantadine toxicity;Renal insufficiency

 

数据来源: Karger

 

摘要:

In a patient with chronic renal failure and maintained with regular hemodialysis, the development of neuropsychiatric untoward effects during amantadine therapy was associated with an inordinately elevated plasma level of the drug. It is recommended that in the face of renal inadequacy, adjustment of the dosage of the drug should be done in accordance with the degree of renal dysfunction.

 

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