Bronchodilator and Side Effects of Different Modes of Administration of MetaproterenolInhaled, Oral, and in Combination
作者:
GEORGE MAGUIRE,
CEMIL EMIRGIL,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1986)
卷期:
Volume 291,
issue 3
页码: 168-174
ISSN:0002-9629
年代: 1986
出版商: OVID
关键词: Asthma;Metaproterenol;Bronchodilators
数据来源: OVID
摘要:
Twenty subjects with clinically stable asthma were treated in double-blind crossover manner with inhaled and oral metaproterenol, alone and in combination. The combination of inhaled and oral metaproterenol resulted in a greater degree of bronchodilation than either inhaled or oral alone. Inhaled metaproterenol was not associated with any significant side effects. Oral metaproterenol was associated with a small but significant increase in pulse rate and systolic blood pressure, and a small incidence of unpleasant sensations such as tremor and palpitation. Older subjects were more likely to experience the unpleasant sensations, whereas younger subjects were more likely to experience the increase in pulse rate.
点击下载:
PDF
(533KB)
返 回