首页   按字顺浏览 期刊浏览 卷期浏览 Aminonucleoside Nephrosis in Rats
Aminonucleoside Nephrosis in Rats

 

作者: Adalberto Sessa,   Ferruccio Conte,   Aniello Cioffi,   Giuseppe D’Amico,  

 

期刊: Nephron  (Karger Available online 1975)
卷期: Volume 14, issue 3-4  

页码: 299-308

 

ISSN:1660-8151

 

年代: 1975

 

DOI:10.1159/000180460

 

出版商: S. Karger AG

 

关键词: Aminonucleoside nephrosis;Chronic glomerulonephritis;Electron microscopy;Glomerular permeability;Indomethacin;Podocytes

 

数据来源: Karger

 

摘要:

The concomitant administration of Indomethacin reduced the biochemical signs of the nephrotic syndrome induced in rats by aminonucleoside; in the rats treated with both drugs a morphological picture suggesting activated function of podocytes was found at the electron microscopic examination of the renal glomerular structures, together with the lesions characteristic of the aminonucleoside nephrosis. The possibility is discussed that Indomethacin could modify the permeability of the glomerular capillary wall by stimulating thepodocytes to synthesize basement membrane material.

 

点击下载:  PDF (1079KB)



返 回