Biophysical and Endocrine-Metabolic Changes during Menopausal Hot Flashes: Increase in Plasma Free Fatty Acid and Norepinephrine Levels
作者:
M. Cignarelli,
E. Cicinelli,
M. Corso,
M.R. Cospite,
G. Garruti,
E. Tafaro,
R. Giorgino,
S. Schonauer,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1989)
卷期:
Volume 27,
issue 1
页码: 34-37
ISSN:0378-7346
年代: 1989
DOI:10.1159/000293612
出版商: S. Karger AG
关键词: Menopausal hot flashes;Free fatty acids;Catecholamines;Hormones;Metabolism
数据来源: Karger
摘要:
Thermocutaneous, vascular, metabolic and hormonal changes were investigated during 11 hot flashes from 6 postmenopausal women. The first detectable change was an increase in finger blood flow with a concomitant enhancement of skin conductance. The increase in skin conductance was followed rapidly by a sharp rise in finger temperature. The main endocrine-metabolic changes associated with the above phenomena were a sharp increase in plasma free fatty acids (∼65%), norepinephrine (∼ 100%) and LH (∼20%) levels. Plasma glucose and cortisol tended to be increased but did not reach statistical significance; on the other hand, plasma insulin, glucagon, growth hormone, epinephrine and dopamine remained unchanged.
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