In 323 of 1,620 patients with gastric cancer, the lesion was ≥ 10 cm in maximum diameter. Studies were done with respect to clinicopathologic features and the prognosis. Patients with tumors ≥ 10 cm were younger and women patients were more numerous compared to those with tumors < 10cm. Tumors were more advanced and noncurative resection was usually done for these patients. A multivariate analysis showed that serosal invasion, liver metastasis, lymph node metastasis, operative curability, tissue differentiation, and extended lymph node dissection to be independent prognostic factors. This retrospective study showed that patients with a larger tumor are at an increased risk for tumor advancement and that they will benefit from curative resection and extended lymph node dissect