Rational treatment of pulmonary infections in patients with cystic fibrosis
作者:
Marc Foca,
Sujatha Rajan,
Lisa Saiman,
期刊:
Current Opinion in Infectious Diseases
(OVID Available online 1999)
卷期:
Volume 12,
issue 3
页码: 257-263
ISSN:0951-7375
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
The life expectancy of patients with cystic fibrosis has increased markedly during the past two decades due in large part to improved clinical care, including the use of more effective antimicrobial agents for Pseudomonas. However, the chronic lung disease of CF remains the principal cause of mortality. A growing understanding of the complex interactions between infection and inflammation has led to new approaches for treatment, including chronic use of aerosolized antibiotics, particularly tobramycin, in patients known to be colonized/infected withP. aeruginosaand anti-inflammatory treatments to slow the progression of lung disease.
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