Class‐specific antibodies in young and aged humans against organisms producing superficial fungal infections
作者:
P.G. SOHNLE,
C. COLLINS‐LECH,
K.E. HUHTA,
期刊:
British Journal of Dermatology
(WILEY Available online 1983)
卷期:
Volume 108,
issue 1
页码: 69-76
ISSN:0007-0963
年代: 1983
DOI:10.1111/j.1365-2133.1983.tb04580.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYClass‐specific antibodies (IgG, IgA and IgM) againstCandida albicans, Pityrosporum orbiculareandTrichophyton rubrumwere measured in the serum from twenty‐one young subjects (aged 23–44) and twenty elderly subjects (aged 70‐88) who did not have a history of significant superficial fungal infections. We found that (a) antibody to all three organisms was present in all subjects in both groups, (b) except for a reduced level of IgM antibody againstP. orbicular, the elderly subjects demonstrated humoral responses in these assays similar to those of the young subjects, (c) IgA antibody was present in higher amounts againstC. albicansthan againstP. orbiculareorT. rubrumin both groups, and (d) the proportion of IgM antibody againstT. rubrumwas higher than that against the other two organisms. These findings suggest that the ecology of these three organisms with respect to the normal human host may be reflected in the serological responses agai
点击下载:
PDF
(1385KB)
返 回