Blood pressure during eye surgery under local anesthesia was measured in 186 cases treated in our department. 58 cases showed an increase in blood pressure before the operation in spite of premedication; in 32 of these cases there was a 40% rise in blood pressure. Moreover, 38 cases showed at least one ECG abnormality just before the operation in spite of no past history of heart disorders. To control the blood pressure in these cases, intravenous injection of nitroglycerin (Millisrol) was performed continuously and immediately stabilized the blood pressure.