SPECIFICITY OF PASSIVE SERUM PROTECTION AGAINSTNIPPOSTRONGYLUS BRASILIENSISANDNEMATOSPIROIDES DUBIUSIN MICE
作者:
Paul J Brindley,
Colin Dobson,
期刊:
Australian Journal of Experimental Biology and Medical Science
(WILEY Available online 1983)
卷期:
Volume 61,
issue 1
页码: 37-45
ISSN:0004-945X
年代: 1983
DOI:10.1038/icb.1983.4
出版商: Nature Publishing Group
数据来源: WILEY
摘要:
SummaryFewer and smaller worms were recovered from, and significantly fewer parasite eggs were voided by, mice injected with mouse antiserum raised againstNippostrongylus brasiliensisorNematospiroides dubiusafter infection with the homologous nematode species compared with the control mice. The passive transfer of protective immunity was specific for the species which induced the antibody response in the donor mice. Passively immunized mice infected with the heterologous nematode species harboured the same number of worms, with the same epg output, as parasites in the control mice, but were stunted. Serological cross‐reactions were observed between the two donor antiserum pools andN. dubiusandN. brasiliensisantigens.
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