In Southern Nigeria there is a very high incidence of post-bulbar duodenal ulcers. These often present with a typical intermittent history of abdominal pain frequently referred to the back and episodes of haematemesis or melaena. Perforation and obstructive symptoms are rare.The radiographic features of these ulcers are discussed and attention is drawn to the occasional occurrence of choledochoduodenal fistula and incompetence of the ampulla of Vater.