首页   按字顺浏览 期刊浏览 卷期浏览 Juxtaglomerular Cell Granulation and Renal Cortical Renin Activity in Normal and Adrena...
Juxtaglomerular Cell Granulation and Renal Cortical Renin Activity in Normal and Adrenalectomized Guinea Pigs

 

作者: O. Bucher,   B. Riedel,   Nicole Baechtold-Fowler,   G. Schaechtelin,   P. Petrik,   G. Peters,  

 

期刊: Nephron  （Karger Available online 1974）
卷期: Volume 12, issue 3  

页码: 178-187

 

ISSN:1660-8151

 

年代: 1974

 

DOI:10.1159/000180374

 

出版商: S. Karger AG

 

关键词: Epitheloid cells of afferent arterioles;Granulation of juxtaglomerular cells;Renal cortical renin activity in the guinea pig;rat;and man;Extragranular renin;Mechanism of juxtaglomerular granule formation

 

数据来源: Karger

 

摘要:

In the normal guinea pig, the rennin activity of renal cortical tissue was one tenth of that of the rat. Light microscopy did not reveal juxtaglomerular granules in epitheloid cells, while electron microscopy showed very rare small and pale granules. In adrenalectomized animals, cortical rennin activity increased fourfold 8–12 days after operation. Granules increased more than tenfold and were larger and darker; the rough-surfaced endoplasmic reticulum expanded. Data suggest that normal guinea pig kidney may contain extragranular cytoplasmatic renin, while larger amounts of renin occurring after adrenalectomy are deposited in newly formed granule

 

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