Seizure Elicitation Blocked by Pretreatment with Lidocaine
作者:
D. Devanand,
Harold Sackeim,
期刊:
Convulsive Therapy
(OVID Available online 1988)
卷期:
Volume 4,
issue 3
页码: 225-229
ISSN:0749-8055
年代: 1988
出版商: OVID
关键词: Electroconvulsive therapy;Lidocaine pretreatment;Seizure threshold;Efficacy
数据来源: OVID
摘要:
A patient is reported in whom pretreatment with intravenous lidocaine resulted in failure to elicit a seizure even at stimulus intensity markedly greater than that used successfully at prior and subsequent treatments. Together with one other report, this experience suggests that lidocaine may prevent a seizure by raising the seizure threshold. An alternative explanation is proposed for the classic findings of Ottosson that lidocaine-modified seizures are reduced in therapeutic efficacy.
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