Langerhans’ Cells in Squamous Metaplasia of the Human Uterine Cervix
作者:
Wanda Di Girolamo,
J. Goñi,
R.P. Laguens,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1985)
卷期:
Volume 19,
issue 1
页码: 38-41
ISSN:0378-7346
年代: 1985
DOI:10.1159/000299006
出版商: S. Karger AG
关键词: Human ectocervix;Metaplasia;Langerhans’ cells
数据来源: Karger
摘要:
The number and shape of Langerhans’ cells (LC) were studied by determining cytoplasmic formaldehyde-resistant ATPase activity in whole mounts of normal and meta-plastic human cervical epithelium. In normal epithelium the number of LC per square millimeter was 52.75 ± 2.21. A similar number was found in completely differentiated metaplastic squamous epithelium (49.11 ± 2.42), but their shape was different with less branching processes. When metaplasia was still incomplete, and numerous mucous cells remained, no LC were present. On the basis of these results it is speculated that mucous cells provide a negative chemotactic stimulus which prevents migration of LC into metaplastic epithelium. When the latter is completely squamous it is repopulated by LC in a fashion similar to normal squamous epithel
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