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Monoclonal antibodies to bovine blood group antigens

 

作者: E. M. TUCKER,   L. MÉTÉNIER,   J. GROSCLAUDE,   S. W. CLARKE,   L. KILGOUR,  

 

期刊: Animal Genetics  （WILEY Available online 1986）
卷期: Volume 17, issue 1  

页码: 3-13

 

ISSN:0268-9146

 

年代: 1986

 

DOI:10.1111/j.1365-2052.1986.tb03183.x

 

出版商: Blackwell Publishing Ltd

 

关键词: monoclonal antibodies;bovine blood groups;hybridomas;red cell antigens;cattle

 

数据来源: WILEY

 

摘要:

SummaryHybridomas were made by fusing mouse myeloma cells with spleen cells from mice immunized with bovine red cells. Sixteen cloned lines which secreted haemolytic monoclonal antibodies reacting with antigens in the A, B, F, Z and S blood group systems were established; one of the antibodies identified a new factor in the B system. Extensive tests on red cells from 1000 animals indicated that several of the antibodies are suitable for use in routine blood typing; others are of potential use for genetic studies of the bovine blood group systems.

 

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