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Testicular feminization syndrome in three sibs: emphasis on gonadal neoplasia

 

作者: MICHAEL CONNELL,   HAROLD RAMSEY,   JACQUELINE WHANG-PENG,   PETER WIERNIK,  

 

期刊: The American Journal of the Medical Sciences  （OVID Available online 1973）
卷期: Volume 265, issue 4  

页码: 321-333

 

ISSN:0002-9629

 

年代: 1973

 

出版商: OVID

 

关键词: Seminoma;Pseudohermaphroditism;Testicular feminization syndrome

 

数据来源: OVID

 

摘要:

The testicular feminization syndrome is a variety of male pseudohermaphroditism with characteristic clinical, biochemical, and genetic findings. Three affected sibs are presented. One patient developed a metastatic seminoma and a second patient had a testicular tubular adenoma (Sertoli cell tumor). The pertinent literature is reviewed, and comments regarding treatment are made emphasizing the increased incidence of gonadal malignancy in these patients.

 

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