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Vaccination against hepatitis B in preschool children with Down's syndrome

 

作者: P. VAJRO,   P. LETTERA,   A. FONTANELLA,   C. SBREGLIA,   E. MANZILLO,   R. SARTORIO,   E. GIUDICE,  

 

期刊: Journal of Intellectual Disability Research  （WILEY Available online 1992）
卷期: Volume 36, issue 1  

页码: 77-81

 

ISSN:0964-2633

 

年代: 1992

 

DOI:10.1111/j.1365-2788.1992.tb00472.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

ABSTRACT.Twenty‐nine healthy HBsAg‐ and HBsAb‐negative children with Down's syndrome who were living at home (mean age 42 months; 19 M, 10 F) were vaccinated against hepatitis B virus either with recombinant DNA or plasma‐derived vaccine. Both groups of children responded well to the vaccination schedules, with HBsAb seroconversion rates close to 100%. Vaccination against hepatitis B in preschool children with Down's syndrome is effective in spite of the existing abnormalities of the immune f

 

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