AbstractDespite the nearly universal finding that life event stress is related to psychopathology, the strength of these relationships is weak. In an attempt to increase the strength of the correlation between life event stress and psychopathology, this study evaluated the simultaneous contribution of life event stress and coping style, as well as the independent contribution of each, to psychopathology. Seventy‐six male and 74 female college students served as primary subjects, while an additional 57 male and 60 female college students served as a cross validation sample. Each subject completed the Life Experiences Survey, the Coping Strategies Inventory, and the MMPI. Sex differences were found in the type of coping style related to psychopathology, the relative contributions of coping style and negative life stress to psychopathology, and the percentage of variance accounted for in psychopathology. Future research was recommended to include other variables, such as chronic life stress and physiological reactivity, and to control better for such methodological problems as response set