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INFLUENCE OF METHYLPREDNISOLONE ON COMPLEMENT ACTIVITY IN GERMFREE RATS AND ON ANTIBODY ACTIVITY TOESCHERICHIA COLIIN MONOCONTAMINATED RATS

 

作者: A. BAARDSEN,   T. MIDTVEDT,   A. TRIPPESTAD,  

 

期刊: Acta Pathologica Microbiologica Scandinavica Section B Microbiology  （WILEY Available online 1975）
卷期: Volume 83B, issue 1  

页码: 37-44

 

ISSN:0304-131X

 

年代: 1975

 

DOI:10.1111/j.1699-0463.1975.tb00067.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Methylprednisolone;complement activity;antibody activity;germfree life;rats

 

数据来源: WILEY

 

摘要:

By means of radio‐isotope technique, the influence of methylprednisolone treatment on opsonic and bactericidal serum activities againstE. coliwas studied on germfree and monocontaminated rats. Based on the present results it seems unlikely that methylprednisolone impairs the production of complement components. A slight suppression of antibody activity was only found in markedly wasted monocontaminated rats treated with very high doses of methylprednisolone from the day before contaminatio

 

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