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Warty Hyperkeratoses, Cellular Immune Defect, and Tapetoretinal Degeneration in Poikiloderma Congenitale

 

作者: E. Haneke,   E. Gutschmidt,  

 

期刊: Dermatology  （Karger Available online 1976）
卷期: Volume 152, issue 6  

页码: 331-336

 

ISSN:1018-8665

 

年代: 1976

 

DOI:10.1159/000251279

 

出版商: S. Karger AG

 

关键词: Poikiloderma congenitale;Warty hyperkeratosis;Cellular immune defect;Tapetoretinal degeneration

 

数据来源: Karger

 

摘要:

Report of a 13-year-old girl suffering from poikiloderma congenitale with warty hyperkeratoses, increased susceptibility to infections and tapetoretinal degeneration. The diminished PHA lymphocyte stimulation is an indicator of an immune cellular defect which is probably the cause of the frequent infections. The significance of keratotic lesions with regard to possible cancer development in later life is discussed.

 

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