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Pulmonary Alveolar Proteinosis and Disseminated Atypical Mycobacteriosis in a Patient with Busulfan Lung

 

作者: Kentaro Watanabe,   Katsuo Sueishi,   Kenzo Tanaka,   Nobuhiko Nagata,   Nobuyuki Hirose,   Nobuaki Shigematsu,   Shunji Miake,   Minoru Yoshida,  

 

期刊: Pathology International  （WILEY Available online 1990）
卷期: Volume 40, issue 1  

页码: 63-66

 

ISSN:1320-5463

 

年代: 1990

 

DOI:10.1111/j.1440-1827.1990.tb01530.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Alveolar proteinosis;Chronic granulocytic leukemia;Disseminated atypical mycobacteriosis;Busulfan lung

 

数据来源: WILEY

 

摘要:

A 32‐year‐old Japanese man with chronic granulocytic leukemia died of respiratory failure. Autopsy revealed alveolar proteinosis and pulmonary fibrosis, complicated by disseminated atypical mycobacteriosis. Epithelial hyper‐plasia caused by busulfan therapy was probably responsible for the induction of excessive surfactant production, resulting in alveolar proteinosis, and the immunosuppres‐sive state due to chronic granulocytic leukemia was probably related to the induction of disseminated atypical mycobacteriosis. Acta Pathol Jpn 40: 63

 

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