Recent developments in mycobacterial research
作者:
Andries Steyn,
John Chan,
Vijay Mehra,
期刊:
Current Opinion in Infectious Diseases
(OVID Available online 1999)
卷期:
Volume 12,
issue 5
页码: 415-424
ISSN:0951-7375
年代: 1999
出版商: OVID
数据来源: OVID
摘要:
Tuberculosis remains a major health problem in the world, which is compounded further by the alarmingly high rate ofM. tuberculosisinfections in AIDS patients. Thus, there is an urgent need to advance our understanding of the mycobacterium to develop new drugs. The extraordinary recent developments in mycobacterial genetic research, particularly in genomics will greatly facilitate this goal. The knowledge of the entire genome sequence ofM. tuberculosiswill help in designing new chemotherapeutic and immunotherapeutic interventions. This review highlights recent developments in genomics, mycobacterial genetics, novel vaccine strategies, and our understanding of tuberculous dormancy.
返 回