Cytogenetic Findings in Moderate and Severe Mental Retardation A Study of an Institutionalized Population of 1991 Patients
作者:
J. P. FRYNS,
A. KLECZKOWSKA,
E. KUBIEŃ,
H. VAN DEN BERGHE,
期刊:
Acta Pædiatrica
(WILEY Available online 1984)
卷期:
Volume 73,
issue 1
页码: 3-23
ISSN:0803-5253
年代: 1984
DOI:10.1111/j.1651-2227.1984.tb10001.x
出版商: Blackwell Publishing Ltd
关键词: mental retardation;chromosomal anomalies;fragile X syndrome
数据来源: WILEY
摘要:
AbstractThe cytogenetic data of a large scale study in an institutionalized population of 1991 moderately and severely mentally retarded patients are presented. In 21.3% of these patients a chromosomal aberration was diagnosed (14.9% Down syndrome patients and 3.5%“other chromosomal anomalies”). A fragile X screening was performed in 354 males, and was found to be positive in 57 (16.1% positive). Different chromosomal variants were present in another 6% of this population. Detailed results are presented on the different groups of chromosomal aberrati
点击下载:
PDF
(998KB)
返 回