Steroid structure and steroid activity
作者:
J. ELKS,
期刊:
British Journal of Dermatology
(WILEY Available online 1976)
卷期:
Volume 94,
issue 1
页码: 3-13
ISSN:0007-0963
年代: 1976
DOI:10.1111/j.1365-2133.1976.tb02264.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYThe diverse biological effects associated with naturally occurring steroids are reviewed, with particular reference to the effect upon biological activity of changes in chemical structure. The motives for synthetic modification of the natural products are discussed and are illustrated by reference to the development of systemic and topical anti‐inflammatory agents, with improved potency and reduced side‐effe
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