A Case of Late Onset Lipid Storage Myopathy
作者:
P. Pinelli,
M. Poloni,
G. Nappi,
R. Scelsi,
期刊:
European Neurology
(Karger Available online 1975)
卷期:
Volume 13,
issue 3
页码: 273-284
ISSN:0014-3022
年代: 1975
DOI:10.1159/000114683
出版商: S. Karger AG
关键词: Late onset myopathy;Lipid storage myopathy;Type I fibre atrophy;Prednisone therapy
数据来源: Karger
摘要:
A 65-year-old woman showed the clinical picture of a myogenic myopathy, confirmed electromyographically. Detailed histopathological, histochemical and ultrastructural studies were performed on deltoid and quadriceps femoris biopsy specimens. Many muscle fibres were found to contain vacuolar spaces with lipid droplets: perivascular inflammatory changes were also observed. The affected fibres were consistently type I. Under the electron microscope the fibres contained large numbers of lipid droplets, usually next to normal mitochondria. A slight improvement occurred after prednisone therapy.
点击下载:
PDF
(1425KB)
返 回