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DNA and DNA + Histone Hydrolysis by Guinea Pig Epidermal Enzymes

 

作者: Teruo Miyagawa,   Harukuni Urabe,  

 

期刊: Dermatology  （Karger Available online 1976）
卷期: Volume 153, issue 6  

页码: 346-351

 

ISSN:1018-8665

 

年代: 1976

 

DOI:10.1159/000251145

 

出版商: S. Karger AG

 

关键词: Chromatin digestion;DNase attack on chromatin DNA;Histone protease activity

 

数据来源: Karger

 

摘要:

An acid deoxyribonuclease of guinea pig epidermis hydrolyzes chromatin DNA as well as histone-free DNA. The enzyme degrades approximately 50% of chromatin DNA, while it degrades 90% of histone-free DNA. Guinea pig epidermal extract contains proteolytic activity for histone or chromatin with a pH optimum at around 8.0.

 

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